In vitro and in vivo protective efficacies of antibodies that neutralize the RNA N-glycosidase activity of Shiga toxin 2.Jeong, Kwang-il.
Sheoran, Abhineet S.
Backgound: Shiga toxin 2 (Stx2), one of two Stx liberated by Stx-producing Escherichia coli, is composed of an A subunit monomer and a B subunit pentamer, and is directly linked with hemolytic uremic syndrome in children. The pentameric B subunit binds to its cell surface receptor Gb3 for toxin internalization, and the A subunit follows i... read more
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- Jeong, Kwang-il, Susan Chapman-Bonofiglio, Pradeep Singh, Jongo Lee, Saul Tzipori, and Abhineet S. Sheoran. "In vitro and in vivo protective efficacies of antibodies that neutralize the RNA N-glycosidase activity of Shiga toxin 2." BMC Immunology 11, no. 1 (12, 2010): 1-9.