Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity.Kaplan, David, 1953-
DesRochers, Teresa M.
The staggering cost of bringing a drug to market coupled with the extremely high failure rate of prospective compounds in early phase clinical trials due to unexpected human toxicity makes it imperative that more relevant human models be developed to better predict drug toxicity. Drug-induced nephrotoxicity remains especially difficult to predict in both pre-clinical and clinical settings and is o... read more
- Tissue engineering.
- Human anatomy--Models.
- Biomedical materials.
- Tufts University. Department of Biomedical Engineering.
- Permanent URL
- Original publication
- DesRochers, T. M., L. Suter, A. Roth and D. L. Kaplan (2013). "Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity." PLoS ONE 8(3). doi: 10.1371/journal.pone.0059219.