Synthetic bioreducible lipid-based nanoparticlesfor miRNA delivery to mesenchymal stem cells to induceneuronal differentiation.

Wang, Ming.
Takeda, Yuji S.
Xu, Qiaobing.
Deng, Pu.

MicroRNA (miRNA) functions in tissue regeneration and determines the fate of stem cells. Nanoparticle-based miRNA delivery systems for therapeutic applications have been studied in clinical settings. However, gene delivery to stem cells is still a challenging issue. Lipid-like nanoparticles produced using combinatorial approaches have recently been used for delivery of a variety of biologics. In t... read more

Stem cells.
Tufts University. Department of Biomedical Engineering.
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Original publication
Takeda, Y. S., Wang, M., Deng, P. and Xu, Q. (2016), Synthetic bioreducible lipid-based nanoparticles for miRNA delivery to mesenchymal stem cells to induce neuronal differentiation. Bioengineering & Translational Medicine. doi:10.1002/btm2.10021.
ID: tufts:18443
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