Neuronal differentiation of human mesenchymal stem cells using exosomes derived from differentiating neuronal cells.

Takeda, Yuji S.
Xu, Qiaobing.

Exosomes deliver functional proteins and genetic materials to neighboring cells, and have potential applications for tissue regeneration. One possible mechanism of exosome-promoted tissue regeneration is through the delivery of microRNA (miRNA) In this study, we hypothesized that exosomes derived from neuronal progenitor cells contain miRNAs that promote neuronal differentiation. We treated mesenc... read more

Mesenchymal stem cells.
Regeneration (Biology)
Spinal cord--Wounds and injuries.
Tufts University. Department of Biomedical Engineering.
Permanent URL
Original publication
Takeda YS, Xu Q (2015) Neuronal Differentiation of Human Mesenchymal Stem Cells Using Exosomes Derived from Differentiating Neuronal Cells. PLoS ONE 10(8): e0135111. doi:10.1371/journal.pone.0135111.
ID: tufts:18446
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