Intact β-Cryptoxanthin Prevention of Cigarette Smoke-Induced Inflammatory Lung Lesions Independent of Carotenoid Cleavage Enzymes and Mechanistic Understanding of Sirtuin 1 Activity

Chiaverelli, Rachel.

Abstract: Cigarette smoke (CS) inhalation remains a major public health problem. Chronic inflammation induced by CS is known to be the underlying mechanism for many diseases. Inflammation from CS-exposure has been shown to lead to bronchitis and emphysema, which together, chronically, lead to irreversible damage and chronic obstructive pulmonary disease (COPD). COPD remains a leading cause of hosp... read more

Gerald J. & Dorothy R. Friedman School of Nutrition Science and Policy.
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