A Possible link between Aβ42 production associated with Alzheimer's Disease and SIRT1

Barry, Walter
2009

Alzheimer's, a neurological disease commonly associated with aging, is believed to be driven by the improper clearance and thereby buildup of the 42 residue Aβ peptide. SIRT1 has a demonstrated role as a regulator of metabolism and the process of aging. Prior in virto experiments have shown a protective role of SIRT1 against neurodegenerative diseases like Alzheimer's. Here we show increased level... read more

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Undergraduate honors theses
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Department of Biology
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http://hdl.handle.net/10427/52977
ID: tufts:UA005.010.039.00001
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